Mendelian randomization analysis does not support causal associations of birth weight with hypertension risk and blood pressure in adulthood
- Creator: Zheng, Yan , Huang, Tao , Tai, E-Shyong , Koh, Woon-Puay , Dorajoo, Rajkumar , Saw, Seang-Mei , Sabanayagam, Charumathi , Wong, Tien Yin , Gupta, Preeti , Rossing, Peter , Ahluwalia, Tarunveer S. , Vinding, Rebecca K. , Wang, Tiange , Bisgaard, H , Bønnelykke, K , Wang, Y , Graff, M , Voortman, T , van Rooij, FJA , Hofman, A , van Heemst, D , Noordam, R , Estampador, AC , Mei, Zhendong , Varga, TV , Enzenbach, C , Scholz, M , Thiery, J , Burkhardt, R , Orho-Melander, M , Schulz, CA , Ericson, U , Sonestedt, E , Kubo, M , Sun, Zhonghan , Akiyama, M , Zhou, A , Kilpeläinen, TO , Hansen, T , Kleber, ME , Delgado, G , McCarthy, M , Lemaitre, RN , Felix, JF , Jaddoe, VWV , Zhang, Tao , Wu, Y , Mohlke, KL , Lehtimäki, T , Wang, Carol A. , Pennell, CE , Schunkert, H , Kessler, T , Zeng, L , Willenborg, C , Peters, A , Ellervik, Christina , Lieb, W , Grote, V , Rzehak, P , Koletzko, B , Erdmann, J , Munz, M , Wu, T , He, M , Yu, C , Lecoeur, C , Chai, Jin-Fang , Froguel, P , Corella, D , Moreno, LA , Lai, CQ , Pitkänen, N , Boreham, CA , Ridker, PM , Rosendaal, FR , de Mutsert, R , Power, C , Sim, Xueling , Paternoster, L , Sørensen, TIA , Tjønneland, A , Overvad, K , Djousse, L , Rivadeneira, F , Lee, NR , Raitakari, OT , Kähönen, M , Viikari, J , van Dam, Rob M. , Langhendries, JP , Escribano, J , Verduci, E , Dedoussis, G , König, I , Balkau, B , Coltell, O , Dallongeville, J , Meirhaeghe, A , Amouyel, P
- Resource Type: journal article
- Date: 2020
Novel loci for childhood body mass index and shared heritability with adult cardiometabolic traits
- Creator: Vogelezang, Suzanne , Vinding, RK , Vogel, M , Zeggini, E , Sebert, S , Lind, MV , Brown, CD , Santa-Marina, L , Reischl, E , Frithioff-Bojsoe, C , Meyre, D , Wheeler, E , Ong, K , Nohr, EA , Vrijkotte, TGM , Koppelman, GH , Plomin, R , Njolstad, PR , Dedoussis, GD , Froguel, P , Sorensen, TIA , Jacobsson, B , Freathy, RM , Zemel, BS , Raitakari, O , Vrijheid, M , Feenstra, B , Lyytikainen, L-P , Snieder, H , Kirsten, H , Holt, PG , Heinrich, J , Widen, E , Sunyer, J , Boomsma, DI , Jarvelin, M-R , Koerner, A , Davey Smith, G , Holm, J-C , Atalay, M , Murray, C , Bisgaard, H , McCarthy, MI , Jaddoe, VWV , Grant, SFA , Felix, JF , Bradfield, Jonathon P. , Heiskala, Anni , Horikoshi, Momoko , Fedko, Iryna O. , Vilor-Tejedor, Natalia , Cousminer, Diana L. , Standl, Marie , Wang, Carol A. , Viikari, Jorma , Geller, Frank , Iniguez, Carmen , Ahluwalia, Tarunveer S. , Pitkanen, N , Chesi, A , Bacelis, J , Yengo, L , Torrent, M , Ntalla, I , Helgeland, O , Selzam, S , Vonk, JM , Zafarmand, MH , Curtin, John A. , Heude, B , Farooqi, IS , Alyass, A , Beaumont, RN , Have, CT , Rzehak, P , Bilbao, JR , Schnurr, TM , Barroso, I , Bonnelykke, K , Lakka, Timo A. , Beilin, LJ , Carstensen, L , Charles, M-A , Chawes, B , Clement, K , Closa-Monasterolo, R , Custovic, A , Eriksson, JG , Escribano, J , Groen-Blokhuis, M , Grarup, Niels , Grote, V , Gruszfeld, D , Hakonarson, H , Hansen, T , Hattersley, AT , Hollensted, M , Hottenga, J-J , Hypponen, E , Johansson, S , Joro, R , Scholz, Markus , Kahonen, M , Karhunen, V , Kiess, W , Knight, BA , Koletzko, B , Kuehnapfel, A , Landgraf, K , Langhendries, J-P , Lehtimaki, T , Leinonen, JT , van der Most, Peter J. , Li, A , Lindi, V , Lowry, E , Bustamante, M , Medina-Gomez, C , Melbye, M , Michaelsen, KF , Morgen, CS , Mori, TA , Nielsen, TRH , Monnereau, Claire , Niinikoski, H , Oldehinkel, AJ , Pahkala, K , Panoutsopoulou, K , Pedersen, O , Pennell, CE , Power, C , Reijneveld, SA , Rivadeneira, F , Simpson, A , Stergiakouli, Evie , Sly, PD , Stokholm, J , Teo, KK , Thiering, E , Timpson, NJ , Uitterlinden, AG , van Beijsterveldt, CEM , van Schaik, BDC , Vaudel, M , Verduci, E
- Resource Type: journal article
- Date: 2020
A trans-ancestral meta-analysis of genome-wide association studies reveals loci associated with childhood obesity
- Creator: Bradfield, Jonathan P. , Vogelezang, Suzanne , Felix, Janine F. , Chesi, Alessandra , Helgeland, Øyvind , Horikoshi, Momoko , Karhunen, Ville , Lowry, Estelle , Cousminer, Diana L. , Ahluwalia, Tarunveer S. , Thiering, Elisabeth , Boh, Eileen T-H. , Zafarmand, Mohammad H. , Vilor-Tejedor, Natalia , Wang, Carol A. , Joro, Raimo , Chen, Zhanghua , Gauderman, William J. , Pitkänen, Niina , Parra, Esteban J. , Pennell, Craig E. , Fernandez-Rhodes, Lindsay , Alyass, A , Monnereau, C , Curtin, JA , Have, CT , McCormack, SE , Hollensted, M , Frithioff-Bøjsøe, C , Valladares-Salgado, A , Peralta-Romero, J , Teo, YY , Standl, M , Leinonen, JT , Holm, JC , Peters, T , Vioque, J , Vrijheid, M , Simpson, A , Custovic, A , Vaudel, M , Canouil, M , Lindi, V , Atalay, M , Kähönen, M , Raitakari, OT , van Schaik, BDC , Berkowitz, RI , Cole, SA , Voruganti, VS , Wang, Y , Highland, HM , Comuzzie, AG , Butte, NF , Justice, AE , Gahagan, S , Blanco, E , Lehtimäki, T , Lakka, TA , Hebebrand, J , Bonnefond, A , Grarup, N , Froguel, P , Lyytikäinen, LP , Cruz, M , Kobes, S , Hanson, RL , Zemel, BS , Hinney, A , Teo, KK , Meyre, D , North, KE , Gilliland, FD , Bisgaard, H , Bustamante, M , Bonnelykke, K , Rivadeneira, F , Uitterlinden, AG , Baier, LJ , Vrijkotte, TGM , Heinrich, J , Sørensen, TIA , Saw, SM , Pedersen, O , Hansen, T , Eriksson, J , Widén, E , McCarthy, MI , Njølstad, PR , Power, C , Hyppönen, E , Sebert, S , Brown, CD , Järvelin, MR , Timpson, NJ , Johansson, S , Hakonarson, H , Jaddoe, VWV
- Resource Type: journal article
- Date: 2019
Association of Birth Weight With Type 2 Diabetes and Glycemic Traits: A Mendelian Randomization Study
- Creator: Huang, Tao , Wang, Tiange , Voortman, Trudy , Sabanayagam, C , Tai, E-S , Mohlke, KL , Mackey, DA , Gruszfeld, D , Deloukas, P , Tucker, KL , Fumeron, F , Bonnelykke, K , Rossing, P , Noordam, Raymond , Estruch, R , Ordovas, JM , Arnett, DK , Meirhaeghe, A , Amouyel, P , Cheng, C-Y , Sim, X , Teo, YY , van Dam, RM , Koh, W-P , Frazier-Wood, Alexis , Orho-Melander, M , Loeffler, M , Kubo, M , Thiery, J , Mook-Kanamori, DO , Mozaffarian, D , Psaty, BM , Franco, OH , Wu, T , North, KE , Scholz, Markus , Smith, GD , Chavarro, JE , Chasman, DI , Qi, L , Sonestedt, Emily , Akiyama, Masato , Dorajoo, Rajkumar , Zhou, Ang , Kilpeläinen, Tuomas O. , Kleber, Marcus E. , Zheng, Yan , Wang, Carol A. , Godfrey, KM , Lemaitre, R , Felix, JF , Shi, Y , Gupta, P , Khor, C-C , Lehtimaki, T , Wang, CA , Tiesler, CMT , Ellervik, Christina , Thiering, E , Standl, M , Rzehak, P , Marouli, E , He, M , Lecoeur, C , Corella, D , Lai, C-Q , Moreno, LA , Pitkanen, N , Li, Xiang , Boreham, CA , Zhang, T , Saw, SM , Ridker, PM , Graff, M , Van Rooij, FJA , Uitterlinden, AG , Hofman, A , van Heemst, D , Rosendaal, FR , Gao, Meng , de Mutsert, R , Burkhardt, R , Schulz, C-A , Ericson, U , Kamatani, Y , Yuan, J-M , Power, C , Hansen, T , Sorensen, TIA , Tjonneland, A , Fang, Zhe , Overvad, K , Delgado, G , Cooper, C , Djousse, L , Rivadeneira, F , Jameson, K , Zhao, W , Liu, J , Lee, NR , Raitakari, O , Chai, Jin-Fang , Kahonen, M , Viikari, J , Grote, V , Langhendries, J-P , Koletzko, B , Escribano, J , Verduci, E , Dedoussis, G , Yu, C , Tham, YC , Ahluwalia, Tarun veer S. , Lim, B , Lim, SH , Froguel, P , Balkau, B , Fink, NR , Vinding, RK , Sevelsted, A , Bisgaard, H , Coltell, O , Dallongeville, J , Wang, Yujie , Gottrand, F , Pahkala, K , Niinikoski, H , Hypponen, E , Pedersen, O , Marz, W , Inskip, H , Jaddoe, VV , Dennison, E , YinWong, T
- Resource Type: journal article
- Date: 2019
Phenome-wide association analysis of LDL-cholesterol lowering genetic variants in PCSK9
- Creator: Schmidt, Amand F. , Holmes, Michael V. , Preiss, David , Swerdlow, Daniel I. , Denaxas, Spiros , Fatemifar, Ghazaleh , Faraway, Rupert , Finan, Chris , Valentine, Dennis , Fairhurst-Hunter, Zammy , Hartwig, Fernando Pires , Horta, Bernardo Lessa , Hypponen, Elina , Power, Christine , Moldovan, Max , van Iperen, Erik , Hovingh, Kees , Demuth, Ilja , Norman, Kristina , Steinhagen-Thiessen, Elisabeth , Hancock, Stephen , Attia, John , Holliday, Elizabeth , Scott, Rodney , Teumer, A , Baumeister, S , Doerr, M , Lerch, MM , Voelker, U , Voelzke, H , Ward, J , Pell, JP , Meade, T , Christophersen, IE , Maitland-van der Zee, AH , Baranova, EV , Young, R , Ford, I , Campbell, A , Padmanabhan, S , Bots, ML , Grobbee, DE , Froguel, P , Thuillier, D , Roussel, R , Bonnefond, A , Cariou, B , Smart, M , Bao, Y , Kumari, M , Mahajan, A , Hopewell, JC , Seshadri, S , Dale, C , Costa, RPE , Ridker, PM , Chasman, DI , Reiner, AP , Ritchie, MD , Lange, LA , Cornish, AJ , Dobbins, SE , Hemminki, K , Kinnersley, B , Sanson, M , Labreche, K , Simon, M , Bondy, M , Law, P , Speedy, H , Allan, J , Li, N , Went, M , Weinhold, N , Morgan, G , Sonneveld, P , Nilsson, B , Goldschmidt, H , Sud, A , Engert, A , Hansson, M , Hemingway, H , Asselbergs, FW , Patel, RS , Keating, BJ , Sattar, N , Houlston, R , Casas, JP , Hingorani, AD , Demuth, Juri , Bertram, L , Lill, CM , Coassin, S , Willeit, J , Kiechl, S , Willeit, K , Mason, D , Wright, J , Morris, R , Wanamethee, G , Whincup, P , Ben-Shlomo, Y , McLachlan, S , Price, JF , Kivimaki, M , Welch, C , Sanchez-Galvez, A , Marques-Vidal, P , Nicolaides, A , Panayiotou, AG , Onland-Moret, NC , van der Schouw, YT , Matullo, G , Fiorito, G , Guarrera, S , Sacerdote, C , Wareham, NJ , Langenberg, C , Scott, RA , Luan, J , Bobak, M , Malyutina, S , Pajak, A , Kubinova, R , Tamosiunas, A , Pikhart, H , Grarup, N , Pedersen, O , Hansen, T , Linneberg, A , Jess, T , Cooper, J , Humphries, SE , Brilliant, M , Kitchner, T , Hakonarson, H , Carrell, DS , McCarty, CA , Lester, KH , Larson, EB , Crosslin, DR , de Andrade, M , Roden, DM , Denny, JC , Carty, C , Schofield, P , O'Donnell, M , Yusuf, S , Chong, M , Pare, G , van der Harst, P , Said, MA , Eppinga, RN , Verweij, N , Snieder, H , Christen, T , Mook-Kanamori, DO , Gustafsson, S , Lind, L , Ingelsson, E , Pazoki, R , Franco, O , Hofman, A , Uitterlinden, A , Dehghan, A
- Resource Type: journal article
- Date: 2019